Cholecystokinin-like peptide is a modulator of a crustacean central pattern generator

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Cholecystokinin-like peptide is a modulator of a crustacean central pattern generator.

The presence, release, and physiological effects of a cholecystokinin(CCK)-like peptide within the stomatogastric ganglion (STG) of the lobster, Panulirus interruptus, are described. Indirect immunofluorescence with 2 antisera raised against CCK8 was used to determine the distribution of CCK-like immunoreactivity (CCKLI) in the stomatogastric nervous system. CCKLI was demonstrated in the input ...

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Crustacean motor pattern generator networks.

Crustacean motor pattern-generating networks have played central roles in understanding the cellular and network bases of rhythmic motor patterns for over half a century. We review here the four best investigated of these systems: the stomatogastric, ventilatory, cardiac, and swimmeret systems. Generally applicable observations arising from this work include (1) neurons with active, endogenous ...

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Partial purification, tissue distribution and modulatory activity of a crustacean cholecystokinin-like peptide.

Reversed-phase chromatography was used to separate several forms of cholecystokinin-like peptides (CCKLP) from the pericardial organs (PCOs) of the spiny lobster Panulirus interruptus. Fast protein liquid chromatography of PCOs, stomatogastric ganglia (STGs) and eyestalks revealed five peaks of CCKLP (peaks A-E) that were common to all three tissues, as well as two additional peaks (peaks F and...

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Crustacean cardioactive peptide is a modulator of oviduct contractions in Locusta migratoria.

Crustacean cardioactive peptide (CCAP) stimulates the contractions of locust oviducts. CCAP increased the basal tonus and increased the frequency and amplitude of phasic contractions, as well as the amplitude of neurally-evoked oviduct contractions in a dose-dependent manner. Oviducts from Vth instar larvae and adult locusts aged 10 days or less, were more sensitive to CCAP than oviducts from a...

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Computational modelling of a Central Pattern Generator

Central Pattern Generators (CPGs) are small, rhythmically active networks, which control simple repetitive behaviours, in both vertebrates and invertebrates. Research on CPGs aims at understanding how the periodic pattern is generated and modulated, by investigating the intrinsic and synaptic properties of the component neurons. In this study, we present a mathematical, biophysically-realistic ...

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ژورنال

عنوان ژورنال: The Journal of Neuroscience

سال: 1989

ISSN: 0270-6474,1529-2401

DOI: 10.1523/jneurosci.09-07-02486.1989